We already know Madagascar is a prime location for Uncharted 4, due to it being where the Pirate Every made his treasure laden home. However, Uncharted 4 looks like it could be one of the more varied games in the series geographically.
Joining Madagascar is its nearest neighbour Africa, with a recent trailer showing a positively safari-like experience for the gang. We’ve also seen what looks like Nathan’s childhood home in Manhattan and a very Celtic looking gravestone suggesting either an English, Irish, Welsh, Scottish or even French location.
That’s not as improbable as it might seem either, as the Pirate Every was English, originally coming from the UK’s West Country. He definitely visited both Ireland and Scotland during the Nine Year’s War when he served in the Navy.